Search results for "mass [excited state]"

showing 10 items of 5250 documents

Clinical and biochemical markers of visceral adipose tissue activity: Body mass index, visceral adiposity index, leptin, adiponectin, and matrix meta…

2018

Context: The correlation between aggressive prostate cancer and obesity mainly based on body mass index (BMI) and pathology after surgery remains controversial. Aims: The aim of the study was to correlate BMI, visceral adiposity index (VAI), and the plasmatic levels of leptin, adiponectin, and matrix metalloproteinase-3 (MMP-3), and biomarkers of adipose tissue function, with the detection of Gleason patterns 4 and 5 at biopsy. Subjects and Methods: Consecutive patients with prostate cancer at 12-core transrectal biopsy were enrolled. BMI, waist circumference (WC), blood samples to evaluate the plasmatic levels of triglycerides (TG) and high-density lipoproteins (HDL), adiponectin, leptin, …

medicine.medical_specialtyobesityProstate biopsyUrology030232 urology & nephrologyAdipose tissuebody mass indexlcsh:RC870-923GastroenterologyleptinGleason patternmatrix metalloproteinase-303 medical and health sciencesProstate cancer0302 clinical medicineInternal medicineBiopsymedicineAdiponectinmedicine.diagnostic_testbusiness.industryLeptinnutritional and metabolic diseaseslcsh:Diseases of the genitourinary system. Urologymedicine.diseaseprostate cancervisceral adiposity indexTransrectal biopsy030220 oncology & carcinogenesisOriginal ArticleAdiponectinbusinessBody mass index
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Health-related quality of life after camp-based family obesity treatment: an RCT.

2019

ObjectiveTo compare the effects of a 2-year camp-based immersion family treatment for obesity with an outpatient family-based treatment for obesity on health-related quality of life (HRQoL) in two generations.DesignRandomised controlled trial.SettingRehabilitation clinic, tertiary care hospital and primary care.PatientsFamilies with at least one child (7–12 years) and one parent, both with obesity.InterventionsSummer camp for 2 weeks, with four repetition weekends, or lifestyle school, including four outpatient days over 4 weeks. Behavioural techniques to promote a healthier lifestyle.Main outcome measuresChildren’s and parents’ HRQoL were assessed using generic and obesity-specific measure…

medicine.medical_specialtyobesitymedicine.medical_treatmentPsychological intervention030209 endocrinology & metabolismlaw.inventionrehabilitationTreatment and control groups03 medical and health sciences0302 clinical medicineRandomized controlled trialVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Pediatri: 760lawMedicine030212 general & internal medicine1506RehabilitationIntention-to-treat analysisbusiness.industrymedicine.diseasepatient perspectiveObesityPeer reviewPediatrics Perinatology and Child HealthPhysical therapyOriginal ArticlebusinessBody mass indexBMJ paediatrics open
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Acute Effect of Alcohol Intake on Cardiovascular Autonomic Regulation During the First Hours of Sleep in a Large Real-World Sample of Finnish Employe…

2018

Background Sleep is fundamental for good health, and poor sleep has been associated with negative health outcomes. Alcohol consumption is a universal health behavior associated with poor sleep. In controlled laboratory studies, alcohol intake has been shown to alter physiology and disturb sleep homeostasis and architecture. The association between acute alcohol intake and physiological changes has not yet been studied in noncontrolled real-world settings. Objective The aim of this study was to assess the effects of alcohol intake on the autonomic nervous system (ANS) during sleep in a large noncontrolled sample of Finnish employees. Methods From a larger cohort, this study included 4098 su…

medicine.medical_specialtysykeAlcoholuni (lepotila)03 medical and health scienceschemistry.chemical_compound0302 clinical medicinewearable electronic deviceInternal medicineHeart rateautonominen hermostomedicineheart rateHeart rate variability030212 general & internal medicinesleepta315Original Paperbusiness.industrysydänautonomic nervous systemheart rate variabilityRepeated measures designta3141217 Medical engineeringuni (biologiset ilmiöt)Sleep in non-human animalsalcohol drinkingPsychiatry and Mental healthchemistryCohortAnalysis of variancealkoholinkäyttöbusinessBody mass index030217 neurology & neurosurgeryJMIR Mental Health
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Hormone Replacement Therapy Associated White Blood Cell DNA Methylation and Gene Expression are Associated With Within-Pair Differences of Body Adipo…

2015

The loss of estrogen during menopause causes changes in the female body, with wide-ranging effects on health. Estrogen-containing hormone replacement therapy (HRT) leads to a relief of typical menopausal symptoms, benefits bone and muscle health, and is associated with tissue-specific gene expression profiles. As gene expression is controlled by epigenetic factors (including DNA methylation), many of which are environmentally sensitive, it is plausible that at least part of the HRT-associated gene expression is due to changes in DNA methylation profile. We investigated genome-wide DNA methylation and gene expression patterns of white blood cells (WBCs) and their associations with body compo…

medicine.medical_specialtyvaihdevuodetmedicine.drug_classHormone Replacement TherapyHRTmenopauseGene ExpressionBiologyBody fat percentageepigenetic regulationBody Mass IndexBone DensityInternal medicineGene expressionmedicineLeukocytesHumansgeeniekspressioEpigeneticsGeneGenetics (clinical)kehonkoostumusAdipositybody compositionta1184skeletal muscle compositionObstetrics and Gynecologyta3141DNA MethylationDNA-metylaatio3. Good healthPostmenopausehormone replacement therapyEndocrinologyDifferentially methylated regionsEstrogenPediatrics Perinatology and Child HealthDNA methylationLean body massFemalediscordant monozygotic twin pair designbone mineral contentGenome-Wide Association StudyTwin research and human genetics : the official journal of the International Society for Twin Studies
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Validity and repeatability of the Pediatric Allergy Questionnaire for Athletes (AQUAped) for the screening of atopy.

2020

BACKGROUND High atopy prevalence has been reported in athletes. Having an age-specific questionnaire for predicting atopy is important for an optimal management of young athletes. The study objectives were as follows: (i) developing a scoring system for the Pediatric Allergy Questionnaire for Athletes (AQUAped); (ii) identifying the optimal age target within the range 7-14 years; (iii) assessing AQUAped validity and repeatability in the identified target population. METHODS A total of 133 young athletes (age 7-14 years) were recruited. Following a screening visit, the participants filled AQUAped at baseline (T0) and after 7 days (T1), concomitantly undergoing skin prick testing. Using atopy…

medicine.medical_specialtyvalidityAdolescentImmunologyatopymedicine.disease_causeAtopy03 medical and health sciences0302 clinical medicineSettore MED/38 - Pediatria Generale E SpecialisticachildrenInternal medicineSurveys and QuestionnairesmedicineHypersensitivityImmunology and AllergyHumansMass Screening030212 general & internal medicinerepeatabilityChildSkin Testsyoung athletesReceiver operating characteristicbiologyAthletesbusiness.industryscreeningAQUApedInfant NewbornAeroallergenGold standard (test)Repeatabilitybiology.organism_classificationmedicine.diseaseOptimal management030228 respiratory systemAthletesPediatrics Perinatology and Child HealthPediatric allergybusinessPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and ImmunologyREFERENCES
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Enantioselective determination of plasma protein binding of common amphetamine-type stimulants.

2021

Amphetamine-type stimulants (ATS) like amphetamine ('speed'), methamphetamine ('crystal meth') and 3,4-methylenedioxy-N-methylamphetamine (MDMA, 'ecstasy') represent some of the most frequently abused drugs worldwide. Another less frequently abused ATS is 4-fluoroamphetamine (4-FA). The enantiomers of these four compounds exhibit different pharmacokinetic and pharmacodynamic properties. According to the free drug theory, the pharmacological properties of a substance are dependent on its plasma protein binding (PPB). However, data on PPB of stimulant enantiomers in humans are rare or non-existent. Human plasma samples were spiked with racemic mixtures of the stimulants and subjected to ultra…

medicine.medical_treatmentClinical BiochemistryPharmaceutical ScienceTandem mass spectrometryAnalytical ChemistryPharmacokineticsTandem Mass SpectrometryDrug DiscoverymedicineHumansAmphetamineSpectroscopyChromatographyChemistryIllicit DrugsForensic toxicologyMDMAStereoisomerismMethamphetamineStimulantAmphetamineCentral Nervous System StimulantsEnantiomermedicine.drugChromatography LiquidProtein BindingJournal of pharmaceutical and biomedical analysis
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EMAS position statement: Predictors of premature and early natural menopause.

2019

Simoncini, Tommaso/0000-0002-2971-0079; Chung, Hsin-Fang/0000-0003-3261-5942; Mishra, Gita/0000-0001-9610-5904 WOS:000468709100014 PubMed ID: 31027683 Introduction: While the associations of genetic, reproductive and environmental factors with the timing of natural menopause have been extensively investigated, few epidemiological studies have specifically examined their association with premature (< 40 years) or early natural menopause (40-45 years). Aim: The aim of this position statement is to provide evidence on the predictors of premature and early natural menopause, as well as recommendations for the management of premature and early menopause and future research. Materials and methods…

medicine.medical_treatmentMenopause PrematureTwinsPremature ovarian insufficiencyOVARIAN DEVELOPMENT0302 clinical medicine3123 Gynaecology and paediatricsPregnancyRisk FactorsEpidemiology030212 general & internal medicineFamily historyAetiology030219 obstetrics & reproductive medicineObstetricsEstrogen Replacement TherapySmokingObstetrics and Gynecology3. Good healthEarly menopauseMenopauseParityMenarcheFemaleUnderweightmedicine.symptomMenopausemedicine.medical_specialtyPremature ovarian insufficiencyGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesAGEThinnessmedicineHumansPrematureMenarchePregnancyLIFE-COURSEbusiness.industryREPRODUCTIVE PERIODBody Weightmedicine.diseaseCOGNITIVE FUNCTIONBIRTH-WEIGHTAetiology; Early menopause; Premature ovarian insufficiency; Risk factors; Body Weight; Estrogen Replacement Therapy; Female; Humans; Menarche; Pregnancy; Risk Factors; Smoking; Thinness; Twins; Menopause; Menopause Premature; ParityBODY-MASS INDEXRisk factorsRISK-FACTORSHormone therapyCIGARETTE-SMOKINGbusinessSOCIOECONOMIC POSITIONMaturitas
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Characterization of the synthetic cannabinoid MDMB-CHMCZCA

2016

The synthetic cannabinoid MDMB-CHMCZCA was characterized by various spectroscopic techniques including NMR spectroscopy and tandem mass spectrometry. The synthetic sample was found to be of S-configuration by VCD spectroscopy and comparison of the data with DFT calculations, while ECD spectroscopy was found to be inconclusive in this case. The enantiomeric purity of samples from test purchases and police seizures was assessed by a self-developed chiral HPLC method.

medicine.medical_treatmentNPS010402 general chemistryTandem mass spectrometry01 natural sciencesFull Research Paperlcsh:QD241-441lcsh:Organic chemistrymedicinelcsh:Sciencechiral HPLCSpectroscopyChromatographyChemistry010401 analytical chemistryOrganic ChemistryNuclear magnetic resonance spectroscopy0104 chemical sciencesCharacterization (materials science)Chiral column chromatographyChemistryVCD spectroscopyECD spectroscopylcsh:QCannabinoidEnantiomersynthetic cannabinoidsBeilstein Journal of Organic Chemistry
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Anthropometric indices, lipid profile, and lipopolysaccharide-binding protein levels in metabolic endotoxemia: A case-control study in Calabar Metrop…

2020

Objectives: To determine the anthropometric indices, lipopolysaccharide-binding proteins (LBP), and lipid profile in patients with metabolic endotoxemia. Methods: The study comprised of 47 patients with metabolic endotoxemia (the metabolic endotoxemia group) and 43 controls (the control group). Patients in the metabolic endotoxemia group were categorized further into three subgroups including the normal weight group (n=8), the overweight group (n=12) and the obese group (n=27). Height, weight, waist, and hip circumference were measured, and waist-hip ratio (WHR) and body mass index (BMI) were calculated. LBP was determined by ELISA and total cholesterol, triglycerides, high density lipoprot…

metabolic endotoxemia; gut; microbiota; lipopolysaccharide-binding protein; body mass index; lipid profile; anthropometric indicesmedicine.medical_specialtyVery low-density lipoproteinWaistmedicine.diagnostic_testbusiness.industrylcsh:Medical emergencies. Critical care. Intensive care. First aidlcsh:RC86-88.9General MedicineOverweightmedicine.diseasechemistry.chemical_compoundEndocrinologyHigh-density lipoproteinchemistryInternal medicineLow-density lipoproteinmedicinelipids (amino acids peptides and proteins)medicine.symptomLipid profilebusinessBody mass indexDyslipidemiaJournal of Acute Disease
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Existence of optimal transport maps in very strict CD(K,∞) -spaces

2018

We introduce a more restrictive version of the strict CD(K,∞) -condition, the so-called very strict CD(K,∞) -condition, and show the existence of optimal maps in very strict CD(K,∞) -spaces despite the possible lack of uniqueness of optimal plans. peerReviewed

metric measure spacesdifferentiaaligeometriaRicci curvatureoptimal mass transportationvariaatiolaskentaexistence of optimal mapsmittateoriametriset avaruudetbranching geodesics
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